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Genomic mutations over the course of metastatic MPNST. (A, B) Nonsynonymous exonic somatic called variants in each sample. Variants in the primary tumors are depicted in the blue circles. Mutations in the bone metastasis are depicted in the yellow circle. Mutations in the lung metastases are depicted in the red circles. TRIM genes, including TRIM23, mutated in the samples have been bolded.
