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. 2019 Apr 11;40(4):369–379. doi: 10.1093/asj/sjz109

Figure 4.

Figure 4.

Quantitative polymerase chain reaction results comparing the relative expression of genes associated with enhanced fibrotic activity in CD26-positive, CD26-negative, and unsorted (CD45-CD235a-CD31-) fibroblasts isolated from irradiated breast tissue specimens. All experiments were run in triplicate and data were standardized to glyceraldehyde 3-phosphate dehydrogenase expression for statistical analysis. There were higher levels of expression of (A), IL8 (B), TGF-β1 (C), COL1A1, and (D) TIMP4-positive fibroblasts compared with CD26-negative, and CD26-positive fibroblasts compared with unsorted fibroblasts (P ≤ 0.05*; P ≤ 0.01**; P ≤ 0.001***; P ≤ 0.0001****).