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. 2020 Jan 21;367(5):fnaa012. doi: 10.1093/femsle/fnaa012

Table 1.

Location and between-isolate range of the antimicrobial's MIC advancement-point bacterial density (AP), after which the MIC sharply increased, observed for each of the antimicrobial–bacterial (sub)species combinations.

The antimicrobial drug MIC's AP observed across n = 4 isolates of the bacterial (sub)species, log10(colony forming units (CFU)/mL)
Mechanism of antibacterial action: antimicrobial drug Escherichia coli Non-typhoidal Salmonella enterica subsp. enterica Staphylococcus aureus Streptococcus pneumoniae
Inhibiting cell-wall synthesis:
Ceftriaxone 5.2–6.3 (range 1.1) 6.2–7.3 (range 1.1) 6.4–7.6 (range 1.2) 5.0–6.5 (range 1.5)
Oxacillin 3.2–4.1 (range 0.9) 3.5–5.5 (range 2.0)
Vancomycin 4.5–7.4 (range 2.9)
Inhibiting DNA replication:
Ciprofloxacin 3.0–5.7 (range 2.7) 3.3–5.2 (range 1.9) 2.2–4.0 (range 1.8)
Inhibiting protein synthesis:
Gentamicin 4.6–5.5 (range 0.9) 4.4–5.0 (range 0.6) 6.7–7.6 (range 0.9) 2.1–2.8 (range 0.7)
Linezolid 4.6–5.7 (range 1.1) 2.2–2.9 (range 0.7)