Fig. 3. Effects of orientin, vitexin, luteolin 7-glucoside (Lu 7-G), apigenin 7-glucoside (Api 7-G), and luteolin on anoctamin-1-mediated Cl– current (IANO1).
(A) Representative current (I)/voltage (V) relationship curves showing the effects of the five compounds on IANO1. Luteolin and Lu 7-G significantly inhibited IANO1. (B) Changes (%) in remaining current at +100 mV caused by the five identified compounds. Luteolin and Lu 7-G had a significant effect on IANO1 at a concentration of 100 μM. ****p < 0.0001, *p < 0.05 compared to the control (n = 4).