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. Author manuscript; available in PMC: 2020 Jun 26.
Published in final edited form as: Exp Clin Psychopharmacol. 2019 May 23;28(2):181–195. doi: 10.1037/pha0000300

Table 3.

Mean (±SEM) response rates (responses/s) on the levers associated with the large magnitude and small magnitude reinforcers during the initial and terminal links following psychostimulant administration.

Amphetamine
Dose Initial Link - Large Reinforcer Initial Link - Small Reinforcer Terminal Link - Large Reinforcer# Terminal Link - Small Reinforcer#
0 mg/kg 1.195 (0.066) 1.728 (0.129) 2.859 (0.264) 3.072 (0.407)
0.25 mg/kg 1.055 (0.107) 1.262 (0.118) 2.703 (0.320) 3.189 (0.406)
0.5 mg/kg* 0.792 (0.063) 0.932 (0.094) 2.001 (0.388) 1.938 (0.399)
1.0 mg/kg* 0.609 (0.070) 0.779 (0.088) 1.867 (0.422) 1.701 (0.514)
Methylphenidate
Dose Initial Link - Large Reinforcer Initial Link - Small Reinforcer^ Terminal Link - Large Reinforcer# Terminal Link - Small Reinforcer#^
0 mg/kg 1.140 (0.122) 1.666 (0.203) 2.282 (0.258) 3.294 (0.329)
0.3 mg/kg 1.255 (0.087) 1.557 (0.064) 2.880 (0.322) 3.304 (0.389)
1.0 mg/kg 0.978 (0.085) 1.216 (0.145) 2.502 (0.317) 2.834 (0.298)
3.0 mg/kg 1.009 (0.098) 1.106 (0.141) 2.027 (0.293) 2.780 (0.308)
Methamphetamine
Dose Initial Link - Large Reinforcer Initial Link - Small Reinforcer Terminal Link - Large Reinforcer# Terminal Link - Small Reinforcer#
0 mg/kg 1.255 (0.134) 1.616 (0.109) 2.772 (0.221) 3.658 (0.348)
0.5 mg/kg* 0.750 (0.098) 0.757 (0.134) 2.076 (0.307) 2.412 (0.388)
1.0 mg/kg* 0.699 (0.194) 0.905 (0.321) 2.183 (0.333) 2.158 (0.431)
2.0 mg/kg* 0.416 (0.094) 0.517 (0.120) 1.362 (0.372) 1.082 (0.275)
*

p < .05, relative to vehicle (main effect of dose).

#

p < .05, relative to the terminal link (main effect of trial component).

^

p < .05, relative to the large, uncertain reinforcer (main effect of reinforcer).