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. 2020 Feb 20;64(9):1900696. doi: 10.1002/mnfr.201900696

Figure 1.

Figure 1

Overview of a) the spermatogenesis, embryogenesis, the corresponding histone‐protamine exchange, and the methylation level of non‐imprinted genes and b) folate related one‐carbon metabolism. DHF, dihydrofolate; THF, tetrahydrofolate; 5,10‐MTHF, 5,10‐methylenetetrahydrofolate; MTHFR, methylenetetrahydrofolate reductase; 5‐MTHF, 5‐methyltetrahydrofolate; MS, methionine synthase;SAM, S‐adenosylmethionine. Dark blue box: proteins; green box: enzymes; yellow box: vitamin/cofactor; light blue box: processes.