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Pharmacokinetic parameters of sirolimus accumulated in cardiac muscles and heart tissue after implantation.
| Parameter (Unit) | LCX cardiac muscles | LAD cardiac muscles | RCA cardiac muscles | Heart |
|---|---|---|---|---|
| AUC (ug·d/L) | 2732.74 | 4157.90 | 7159.28 | 2183.60 |
| Tmax (d) | 1.00 | 1.00 | 1.00 | 90.00 |
| Cmax (ug/L) | 205.07 | 218.20 | 235.85 | 56.50 |
| t1/2 (d) | 39.82 | 22.61 | 17.19 | 26.46 |
