Table 1.

Medulloblastoma classification system in the WHO Classification of Tumors of the Central Nervous System 2016.

Medulloblastoma, genetically defined

WNT‐activated

SHH‐activated, TP53‐wild‐type

SHH‐activated, TP53‐mutant

Non‐WNT/non‐SHH

Group 3 †

Group 4 †

Medulloblastoma, histologically defined

Medulloblastoma, classic

Desmoplastic/nodular medulloblastoma (DN)

Medulloblastoma with extensive nodularity (MBEN)

Large cell/Anaplastic medulloblastoma (LCA)

Medulloblastoma, NOS

^†Provisional category.

Adapted from reference (45).