Table 6.
Predictive values of multiparameter ventilator-associated pneumonia score on Day 1 and Day 3
Clinical D1 | Clinical D1 CXR | Clinical D1 LU | Clinical D3 | Clinical D3 LU | |
---|---|---|---|---|---|
Cut-off | 2 | 3 | 4 | 2 | 5 |
Sensitivity | 0.97 | 0.81 | 0.94 | 1 | 0.94 |
(95% CI) | (0.83–1) | (0.63–0.93) | (0.79–0.99) | (0.89–1) | (0.76–0.99) |
Specificity | 0.33 | 0.66 | 0.67 | 0.33 | 0.83 |
(95% CI) | (0.04–0.78) | (0.22–0.96) | (0.22–0.96) | (0.04–0.78) | (0.36–1) |
Positive likelihood ratio | 1.45 | 2.42 | 2.81 | 1.5 | 5.61 |
(95% CI) | (0.82–2.57) | (0.77–7.6) | (0.9–8.73) | (0.85–2.64) | (0.94–33.67) |
Negative likelihood ratio | 0.1 | 0.29 | 0.1 | 0 | 0.08 |
(95% CI) | (0.01–0.91) | (0.12–0.72) | (0.02–0.41) | (0.02–0.31) | |
Positive predictive value | 0.88 | 0.93 | 0.93 | 0.88 | 0.97 |
(95% CI) | (0.91–0.93) | (0.8–0.97) | (0.82–0.98) | (0.81–0.93) | (0.83–0.99) |
Negative predictive value | 0.66 | 0.4 | 0.66 | 1 | 0.71 |
(95% CI) | (0.71–0.95) | (0.21–0.62) | (0.32–0.9) | (0.38–0.9) | |
AUC (SE) | 0.88 (0.06) | 0.85 (0.07) | 0.91 (0.06) | 0.99 (0.01) | 0.97 (0.03) |
p | 0.004 | 0.008 | 0.002 | 0.0002 | 0.0003 |
Youden J index | 0.68 | 0.51 | 0.6 | 0.95 | 0.79 |
AUC area under the receiver operating characteristic curve, CI confidence intervals, CXR chest X-ray, D day, LU lung ultrasound, SE standard error