Figure 2.

Altered miRNA‐9‐5p level in the injured brain tissues after TBI and intervention with miRNA‐9‐5p oligomers. (a) The temporal profile (from 1 day to 14 days post‐CCI) of miRNA‐9‐5p level in the traumatic foci was determined by qRT‐PCR. The quantitative data were analyzed using the 2^−△△Ct method and the level of miRNA‐9‐5p in sham group was used as control. (n = 5/group) (b) The neurological outcome treated with miRNA‐9‐5p oligomers was evaluated by mNSS (n = 5/group). (**p ＜ .01, ***p ＜ .001 vs. the Sham group; ^# p ＜ .05, ^## p ＜ .01, ^### p ＜ .001 vs. the CCI group.) n: number of rats in each group; CCI: control cortex impact