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. 2020 Feb 11;153(6):e14963. doi: 10.1111/jnc.14963

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© 2020 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of International Society for Neurochemistry

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Over‐expression of miRNA‐9‐5p alleviated the destruction of blood–brain barrier after TBI. (a) The brain water content and (b) Evans blue permeability were detected to evaluate the brain edema at 3‐day post‐CCI (n = 5/group). (c) The immunoblotting and quantitative data of tight junction proteins (d) ZO‐1, (e) Occludin, and (f) Claudin‐5 acquired from traumatic foci at 3‐day post‐CCI (n = 5/group). (*** p < .001 vs. the Sham group; ^# p < .05, ^## p < .01, ^### p < .001 vs. the CCI group.) n: number of rats in each group; TBI: traumatic brain injury; CCI: control cortex impact