Skip to main content
. 2020 Jun 23;64(7):e00482-20. doi: 10.1128/AAC.00482-20

TABLE 1.

Maximum vegetation size over time measured by TTE, vegetation weights, and vegetation MRSA counts for each individual animal in each of the three groups

Group and animal Vegetation size (cm)
Vegetation weight at sacrifice (g) Vegetation MRSA counts at sacrifice (log10 CFU/g)
Baseline (24 h postinfection) 4 h postexebacase 24 h postexebacase 96 h postexebacase
Untreated control
    1 0.45 0.49 NDa ND 0.12 8.52
    2 0.61 0.64 ND ND 0.14 8.71
    3 0.56 0.66 ND ND 0.32 8.54
    4 0.72 0.76 ND ND 0.26 8.87
    5 0.48 0.60 ND ND 0.24 9.00
    Mean (±SD) 0.56 ± 0.21 0.63 ± 0.08 0.22 ± 0.08 8.73 ± 0.21
Daptomycin alone
    1 0.64 0.52 0.60 0.70 0.47 5.28
    2 0.46 0.43 0.48 0.57 0.36 5.49
    3 0.47 0.63 0.54 0.54 0.29 5.88
    4 0.50 0.48 0.57 0.63 0.39 5.56
    Mean (±SD) 0.52 ± 0.08 0.52 ± 0.09 0.55 ± 0.05 0.61 ± 0.07 0.38 ± 0.07 5.55 ± 0.25
Daptomycin + exebacase
    1 0.55 0.52 0.56 0.59 0.18 0.74
    2 0.32 0.61 0.52 0.49 0.16 0.80
    3 0.67 0.61 0.63 0.48 0.18 0.74
    4 0.49 0.63 0.59 0.46 0.19 0.72
    5 0.47 0.47 0.64 0.57 0.21 0.68
    6 0.60 0.61 0.57 0.57 0.24 0.62
    Mean (±SD) 0.52 ± 0.12 0.58 ± 0.06 0.59 ± 0.05 0.53 ± 0.06 0.19 ± 0.03 0.72 ± 0.06
a

ND, not done.