TABLE 1.

Baseline patient characteristics

Parameter	Value(s) for:
	Burkina Faso (n = 299)	Ghana (n = 442)	Mozambique (n = 89)	Tanzania (n = 170)	Total (n = 1,000)
Patient enrollment
Age group [n (%)]
<1 yr	5 (0.5)	1 (0.1)	0	0	6 (0.6)
1 to <5 yr	93 (9.3)	116 (11.6)	2 (0.2)	27 (2.7)	238 (23.8)
5 to <12 yr	143 (14.3)	184 (18.4)	49 (4.9)	74 (7.4)	450 (45.0)
12 to <18 yr	18 (1.8)	64 (6.4)	22 (2.2)	23 (2.3)	127 (12.7)
≥18 yr	40 (4.0)	77 (7.7)	16 (1.6)	46 (4.6)	179 (17.9)
Sex [n (%)]
Male	142 (14.2)	203 (20.3)	47 (4.7)	90 (9.0)	482 (48.2)
Female	157 (15.7)	239 (23.9)	42 (4.2)	80 (8.0)	518 (51.8)
Patient characteristics [median (IQR)]
Age (yr)	6 (4–9)	7.5 (4–13)	11 (9–14)	10 (6–18)	7.5 (5–12)
Body weight (kg)	17 (13–23)	22 (16–42)	31 (26–43)	22 (18–45)	21 (15–38)
Body temperature (°C)	37.4 (36.8–37.7)	37.0 (36.5–38.0)	37.2 (36.5–38.2)	37.7 (37.0–38.9)	37.2 (36.7–38.0)
Pulse rate (beats/min)	100 (87–111)	110 (90–126)	91 (76–111)	99 (84–112)	54 (87–120)
Parasite density (no. of parasites/μl)	960 (440–7,605)	13,466 (1, 210)	23,951 (7,981–74,824)	140 (33–787)	2,537 (297–25,418)
Hemoglobin (g/dl)	10.6 (9.5–11.5)	10.9 (9.8–11.7)	10.8 (9.4–11.9)	10.7 (9.4–11.9)	10.7 (9.6–11.7)
Total bilirubin (μmol/liter)	9.8 (6.6–15.4)	14.0 (9.1–23.6)	17.0 (12.0–25.0)	18.1 (8.3–26.7)	13.4 (8.0–22.9)
ALT (U/liter)	24.3 (18.2–31.1)	20.9 (15.3–31.5)	26.0 (22.0–34.0)	29.1 (21.8–35.6)	24.0 (17.4–33.0)
AST (U/liter)	25.2 (19.1–32.5)	28.4 (22.1–37.9)	33.0 (28.0–44.0)	15.5 (9.6–21.7)	25.9 (18.8–34–9)
BUN (mmol/liter)	2.9 (2.2–3.7)	3.4 (2.4–4.6)	13.0 (11.0–16.0)	6.3 (4.4–10.0)	3.6 (2.6–5.6)
Serum creatinine (μmol/liter)	30.5 (25.0–38.6)	47.8 (38.3–65.3)	44.6 (38.5–53.9)	77.0 (54.0–99.5)	43.9 (32.0–64.0)
Potassium (mmol/liter)	4.2 (4.0–4.4)	3.8 (3.5–4.2)	4.1 (3.9–4.5)	4.4 (3.7–5.7)	4.05 (3.7–4.4)
Chloride (mmol/liter)	102.8 (95.8–105.3)	101.2 (97.0–107.4)	100.0 (99.0–103.0)	108.5 (98.0–114.0)	102.2 (97.0–106.9)