TABLE 1.
Baseline demographic and clinical characteristics of cohorta
| Characteristic | No. (%) |
P | |
|---|---|---|---|
| EOS group (n = 84) | i.v. group (n = 16) | ||
| Median age, yrs (range) | 63 (18–93) | 67 (38–91) | 0.14 |
| Male | 58 (69) | 15 (94) | 0.04 |
| Ethnicity | |||
| New Zealand European | 54 (64) | 10 (63) | 0.89 |
| Maori | 10 (12) | 4 (25) | 0.17 |
| Pacific | 9 (11) | 0 (0) | 0.17 |
| Other | 11 (13) | 2 (13) | 0.95 |
| Median wt, kg (range) | 78 (48–196) | 85 (60–127) | 0.27 |
| Admission specialty | |||
| Cardiology | 18 (21) | 4 (2) | 0.75 |
| General medicine | 18 (21) | 2 (13) | 0.41 |
| Hematology-oncology | 14 (17) | 1 (6) | 0.28 |
| General surgery | 13 (16) | 1 (6) | 0.33 |
| Cardiothoracic surgery | 5 (6) | 3 (19) | 0.08 |
| Other surgical specialties | 8 (10) | 3 (19) | 0.28 |
| Other medical specialties | 8 (10) | 2 (13) | 0.72 |
| Site of infection | |||
| Line | 66 (79) | 14 (88) | 0.41 |
| Peripheral cannula | 45 (54) | 8 (50) | 0.79 |
| PICC | 10 (12) | 2 (13) | 0.94 |
| Central venous line | 8 (10) | 3 (19) | 0.28 |
| Tunneled line or port | 3 (4) | 1 (6) | 0.62 |
| Skin and soft tissue | 8 (10) | 1 (6) | 0.67 |
| Unknown source | 5 (6) | 1 (6) | 0.96 |
| Urinary tract | 3 (4) | 0 (0) | 0.44 |
| Respiratory tract | 2 (2) | 0 (0) | 0.54 |
| Comorbidity | |||
| Cardiovascular disease | 53 (63) | 14 (88) | 0.06 |
| Cancer | 20 (24) | 5 (31) | 0.53 |
| Neurological disease | 18 (21) | 4 (25) | 0.75 |
| Diabetes | 19 (23) | 2 (13) | 0.36 |
| Immunosuppressionb | 16 (19) | 2 (13) | 0.54 |
| Renal disease | 17 (20) | 2 (13) | 0.47 |
| Valvular/congenital heart disease | 8 (10) | 1 (6) | 0.67 |
| Presence of prosthetic material | 15 (18) | 7 (44) | 0.04 |
| Joint or other orthopedic metalware | 7 (8) | 6 (38) | 0.01 |
| Vascular graft | 5 (6) | 1 (6) | 0.96 |
| Cardiac device or valve | 5 (6) | 0 (0) | 0.32 |
| Susceptibility pattern of organism | |||
| PSSA | 26 (31) | 4 (25) | 0.63 |
| MSSA | 54 (64) | 11 (69) | 0.73 |
| MRSA | 4 (5) | 1 (6) | 0.80 |
| Defervescence within 72 h | 80 (95) | 14 (88) | 0.23 |
| No. of positive blood cultures, mean (SD) | 1.6 (0.9) | 2.0 (1.1) | 0.11 |
a
EOS, early oral switch; PICC, peripherally inserted central catheter; PSSA, penicillin-susceptible S. aureus; MSSA, methicillin-susceptible S. aureus; MRSA, methicillin-resistant S. aureus. Data indicate the “numbers (%) of patients” unless noted otherwise in column 1.
b
Corticosteroid equivalent to >20 mg of prednisone for >14 days or other immunosuppressive drugs.