TABLE 1.
Summary statistics of subject demographics and clinical laboratory measures for the overall PK analysis population
| Variablea | N (%) | Mean (SDc ) | Median | Minimum | Maximum |
|---|---|---|---|---|---|
| Age (yr) | 613 (100) | 39.3 (14.8) | 37.0 | 18.0 | 88.0 |
| Wt (kg) | 613 (100) | 78.4 (14.6) | 77.5 | 36.0 | 148 |
| Ht (cm) | 613 (100) | 173 (9.2) | 174 | 137 | 201 |
| BSA (m2) | 613 (100) | 1.92 (0.19) | 1.92 | 1.25 | 2.73 |
| BMI (kg/m2) | 613 (100) | 26.2 (4.5) | 25.6 | 16.0 | 49.3 |
| CLCR (ml/min/1.73 m2) | 613 (100) | 99.8 (28.1) | 113 | 5.5 | 185 |
| Albumin (mg/dl) | 613 (100) | 4.33 (0.46) | 4.40 | 2.20 | 5.30 |
| Race | |||||
| Caucasian | 474 (77.3) | ||||
| Black | 109 (17.8) | ||||
| Asian | 15 (2.4) | ||||
| Otherb | 15 (2.4) | ||||
| Sex | |||||
| Male | 435 (71.0) | ||||
| Female | 178 (29.0) | ||||
| Presence of cirrhosis | |||||
| No | 595 (97.1) | ||||
| Yes | 18 (2.9) | ||||
| Presence of infection | |||||
| No | 402 (65.5) | ||||
| Yes | 211 (34.4) | ||||
| Presence of skin infection | |||||
| No | 483 (78.8) | ||||
| Yes | 130 (21.2) | ||||
| Presence of CABP infection | |||||
| No | 563 (91.8) | ||||
| Yes | 50 (8.2) | ||||
| Presence of uUTI | |||||
| No | 582 (94.9) | ||||
| Yes | 31 (5.1) |
a
BSA, body surface area; BMI, body mass index.
b
Includes American Indian, Alaska native, native Hawaiian, or other Pacific islander.
c
SD, standard deviation.