TABLE 1.
MICs of fenamic acids (tolfenamic acid, flufenamic acid, and meclofenamic acid) and control antibiotics (azithromycin and ceftriaxone) against 45 clinical isolates of N. gonorrhoeae
| Strain | MIC (μg/ml) |
||||
|---|---|---|---|---|---|
| Tolfenamic acid | Flufenamic acid | Meclofenamic acid | Azithromycin | Ceftriaxone | |
| 166 | 4 | 8 | 16 | 0.25 | 0.125 |
| 167 | 2 | 2 | 8 | 16 | 0.015 |
| 168 | 4 | 8 | 16 | 0.25 | 0.06 |
| 169 | 4 | 4 | 8 | 0.25 | 0.06 |
| 171 | 4 | 4 | 8 | 1 | 0.06 |
| 172 | 4 | 4 | 16 | 0.5 | 0.06 |
| 173 | 8 | 8 | 16 | 0.25 | 0.06 |
| 175 | 4 | 4 | 8 | 16 | 0.008 |
| 176 | 4 | 4 | 16 | 0.25 | 0.06 |
| 178 | 4 | 8 | 16 | 1 | 0.06 |
| 179 | 2 | 4 | 4 | 16 | 0.008 |
| 180 | 4 | 4 | 16 | 0.25 | 0.06 |
| 181 | 2 | 2 | 8 | 512 | 0.03 |
| 182 | 4 | 4 | 16 | 1 | 0.06 |
| 184 | 2 | 4 | 8 | 0.5 | 0.06 |
| 185 | 8 | 8 | 16 | 0.25 | 0.06 |
| 186 | 4 | 8 | 16 | 0.25 | 0.06 |
| 187 | 4 | 8 | 8 | 2 | 0.06 |
| 188 | 4 | 4 | 16 | 0.5 | 0.06 |
| 190 | 8 | 8 | 16 | 0.5 | 0.125 |
| 191 | 8 | 8 | 16 | 0.5 | 0.06 |
| 192 | 4 | 8 | 16 | 2 | 0.06 |
| 193 | 8 | 8 | 16 | 1 | 0.06 |
| 194 | 4 | 4 | 8 | 0.25 | 0.5 |
| 197 | 4 | 4 | 4 | 2 | 0.03 |
| 198 | 4 | 8 | 16 | 0.5 | 0.06 |
| 199 | 8 | 8 | 16 | 1 | 0.03 |
| 200 | 8 | 8 | 32 | 0.5 | 0.125 |
| 201 | 8 | 8 | 32 | 0.5 | 0.125 |
| 202 | 8 | 8 | 16 | 8 | 0.015 |
| 203 | 8 | 8 | 32 | 1 | 0.125 |
| 204 | 4 | 8 | 16 | 0.5 | 0.06 |
| 205 | 8 | 8 | 16 | 1 | 0.06 |
| 206 | 8 | 8 | 16 | 1 | 0.06 |
| 207 | 8 | 8 | 32 | 1 | 0.06 |
| 208 | 4 | 4 | 16 | 1 | 0.06 |
| 209 | 4 | 8 | 16 | 1 | 0.06 |
| 211 | 8 | 8 | 16 | 1 | 0.06 |
| 213 | 4 | 4 | 16 | 0.5 | 0.06 |
| 214 | 4 | 4 | 16 | 0.5 | 0.125 |
| WHO F | 8 | 4 | 8 | 0.25 | <0.008 |
| WHO G | 4 | 8 | 8 | 0.5 | <0.008 |
| WHO M | 8 | 4 | 16 | 0.5 | 0.015 |
| WHO N | 4 | 8 | 16 | 0.5 | 0.015 |
| WHO O | 4 | 8 | 16 | 0.5 | 0.015 |
| MIC50 | 4 | 8 | 16 | 0.5 | 0.06 |
| MIC90 | 8 | 8 | 32 | 16 | 0.03 |