TABLE 3.
MICs of fenamic acids (tolfenamic acid, flufenamic acid, and meclofenamic acid), their analogues [dichlorophenyl-ABA, N-(2-amino-4-chlorophenyl) anthranilic acid, N-phenylanthranilic acid, 3-amino-2-(3,5-dimethyl-phenylamino) benzoic acid, 3-amino-2-p-tolylamino benzoic acid, and 3-amino-2-phenylamino benzoic acid], and a control antibiotic (azithromycin) against various species of Lactobacillus
| Strain, description | Tolfenamic acid | Flufenamic acid | Meclofenamic acid | Dichlorophenyl-ABA | N-(2-Amino-4-chlorophenyl) anthranilic acid | N-Phenylanthranilic acid | 3-Amino-2-(3,5-dimethyl-phenylamino) benzoic acid | 3-Amino-2-p-tolylamino benzoic acid | 3-Amino-2-phenylamino benzoic acid | Azithromycin |
|---|---|---|---|---|---|---|---|---|---|---|
| L. gasseri MV-22, isolated in 2007 from the vaginal mucosa of a healthy U.S. woman of childbearing age | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. johnsonii 135-1-CHN, isolated in 2007 from the vaginal mucosa of a Chinese woman | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. gasseri SV-16A-US, isolated in 2007 from the vagina of a healthy U.S. woman | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. jensenii 115-3-CHN, isolated in 2007 from the vaginal mucosa of a healthy Chinese woman | >128 | 64 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. jensenii SJ-7A-US, isolated in 2007 from the vaginal mucosa of a healthy U.S. woman | >128 | 128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. crispatus 125-2-CHN, isolated in 2007 from the vagina of a healthy Chinese woman | >128 | 128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. rhamnosus LMS2-1, isolated from the human gastrointestinal tract | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |
| L. jensenii JV-V16, human isolate from Texas | >128 | 128 | >128 | >128 | >128 | >128 | >128 | >128 | >128 | <1 |