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. 2020 Jun 19;11:1246. doi: 10.3389/fimmu.2020.01246

Figure 1.

Figure 1

Role of antibodies in Sm-p80-based vaccine-mediated protection. (A) Recovered adult male and female worms following passive transfer of purified IgG from baboons immunized with Sm-p80-based vaccine. (B) Liver egg burden and (C) intestine egg burden at necropsy. Hatching rates of eggs recovered from livers (D) and Intestines (E) of mice at necropsy. (F) In vitro killing of S. mansoni schistosomula in the presence of pooled sera from Sm-p80-vaccinated baboons with addition or absence of exogenous complement. All mice were sacrificed at 6 weeks post S. mansoni cercariae challenge. Plotted data represents individual data points with error bars showing means and standard error of the mean.