Table 2.
White matter tract | Regions connected | Major functions | AD | MD | RD | |||
---|---|---|---|---|---|---|---|---|
Left | Right | Left | Right | Left | Right | |||
Arcuate fasciculus—anterior |
Inferior frontal Caudal temporal Inferior parietal (Broca's‐Wernicke's) |
Language | −8.1 | −8.6 | −5.4 | −5.9 | −4.0 | −4.5 |
Arcuate fasciculus—long | −8.8 | −8.4 | −6.0 | −5.9 | −4.6 | −4.6 | ||
Arcuate fasciculus—posterior | −10.2 | −9.6 | −7.0 | −7.0 | −5.4 | −5.6 | ||
Cingulum | Frontal, parietal, medial temporal, subcortical | Emotion, learning, memory | −9.0 | −9.9 | −5.9 | −5.8 | −4.6 | −3.9 |
Corpus callosum | Left‐right cerebral hemispheres | Communication between hemispheres | −8.7 | −8.8 | −5.8 | −5.9 | −4.4 | −4.6 |
Frontal commissural | Frontal‐frontal | Executive | −7.3 | −8.4 | −5.0 | −5.4 | −4.0 | −4.1 |
Inferior fronto‐occipital fasciculus | Frontal‐occipital/temporal | Association, language | −8.6 | −8.9 | −5.8 | −5.9 | −4.4 | −4.4 |
Inferior longitudinal fasciculus | Occipital‐temporal | Visual association/imagery, language | −10.7 | −9.3 | −6.4 | −6.0 | −4.3 | −4.4 |
Pons | Forebrain‐hindbrain (cerebellum) | Arousal, relay sensory/learning information | −7.6 | −5.6 | −4.7 | −3.2 | −3.3 | −2.1 |
Superior longitudinal fasciculus III (ventral) | Supramarginal‐ventral prefrontal | Somatosensory, expressive language, working memory | −7.1 | −8.0 | −4.8 | −5.6 | −3.6 | −4.4 |
Superior longitudinal fasciculus II (major) | Inferior parietal‐dorsolateral prefrontal | Visual‐spatial attention/association | −8.4 | −8.9 | −5.7 | −6.3 | −4.3 | −4.9 |
Superior longitudinal fasciculus I (dorsal) | Superior parietal‐dorsal/medial prefrontal, supplementary motor | Motor task selection/association | −8.0 | −8.6 | −6.0 | −6.2 | −5.0 | −5.1 |
Uncinate fasciculus | Orbitofrontal‐anterior temporal | Limbic association, language (rapid naming) | −3.6 | −5.2 | −2.3 | −3.4 | −1.6 | −2.5 |
Values are in units of 10‐6mm2s‐1 per point of StimQ‐P2 READ. Tracts with significant clusters (see Figure 2) spanning greater than 10% of their volume are in bold.