Table 1.

Model inputs from the literature.

Parameters	Value (SE)		Source
Annual probability of relapse
In the 10 years after first cycle	10.00% (3.06%)		25, 26, 27
After 10 years after first cycle	0%		25, 26, 27
Mortality
Male age group (years)	Continuing smokers	Ex‐smokers
35–44	0.24% (0.40%)	0.18% (0.35%)	28, 29
45–54	0.80% (0.40%)	0.51% (0.73%)	28, 29
55–64	1.94% (0.52%)	1.24% (0.58%)	28, 29
65–74	5.15% (0.82%)	3.08% (0.59%)	28, 29
75+	25.36% (2.04%)	15.12% (1.14%)	28, 29
Female age group (years)	Continuing smokers	Ex‐smokers
35–44	0.14% (0.31%)	0.11% (0.27%)	28, 29
45–54	0.53% (0.33%)	0.34% (0.59%)	28, 29
55–64	1.30% (0.43%)	0.83% (0.48%)	28, 29
65–74	3.45% (0.68%)	2.06% (0.49%)	28, 29
75+	20.79% (1.90%)	12.40% (1.05%)	28, 29
Annual smoking‐related health‐care costs after the first year
Male age group (years)	Continuing smokers	Ex‐smokers
35–44	£54.48 (£0)	£16.57 (£0)	12, 32, 33
45–54	£54.48 (£0)	£16.57 (£0)	12, 32, 33
55–64	£181.97 (£0)	£64.99 (£0)	12, 32, 33
65–74	£315.75 (£0)	£83.82 (£0)	12, 32, 33
75+	£535.22 (£0)	£105.36 (£0)	12, 32, 33
Female age group (years)	Continuing smokers	Ex‐smokers
35–44	£41.31 (£0)	£10.72 (£0)	12, 32, 33
45–54	£41.31 (£0)	£10.72 (£0)	12, 32, 33
55–64	£119.83 (£0)	£40.95 (£0)	12, 32, 33
65–74	£249.03 (£0)	£71.25 (£0)	12, 32, 33
75+	£470.69 (£0)	£103.18 (£0)	12, 32, 33
Annual QALY gain after the first year
Male age group (years)	Continuing smokers	Ex‐smokers
35–44	0.889 (0.007)	0.908 (0.005)	30
45–54	0.841 (0.007)	0.861 (0.005)	30
55–64	0.780 (0.008)	0.803 (0.005)	30
65–74	0.756 (0.008)	0.781 (0.006)	30
75+	0.710 (0.009)	0.737 (0.006)	30
Female age group (years)	Continuing smokers	Ex‐smokers
35–44	0.870 (0.007)	0.889 (0.004)	30
45–54	0.830 (0.007)	0.850 (0.005)	30
55–64	0.763 (0.008)	0.784 (0.005)	30
65–74	0.751 (0.008)	0.773 (0.006)	30
75+	0.676 (0.009)	0.700 (0.007)	30

QALY = quality‐adjusted life‐years; SE = standard error.