Table 1.

Hypotheses for testing responsiveness

1. High positive correlation between SF‐36 or Skindex‐29 change scores and the GRC scale measuring a similar construct

2. Moderate positive correlation between SF‐36 or Skindex‐29 change score and a GRC scale measuring a related, but dissimilar construct

3. Moderate positive correlation between SF‐36 or Skindex‐29 change score and a second GRC scale measuring a related, but dissimilar construct

4. Low positive or negative correlation between SF‐36 or Skindex‐29 change score and a GRC scale measuring an unrelated construct

5. Patients indicating improvement on the associated GRC scale should have a positive mean change score

6. Patients indicating worsening on the associated GRC scale should have a negative mean change score

7. The mean change score of patients indicating improvement should be higher than the mean change score of unchanged patients, which in turn should be higher than the mean change score of worsened patients

Per Medical Outcomes Study Short Form 36 (SF‐36) and Skindex‐29 subscale, these seven hypotheses were tested. If ≥ 75% of these hypotheses were confirmed for a subscale, the subscale was considered responsive to change. GRC, global rating of change.