Table 4.
Testing results of the hypotheses for evaluation of responsiveness. Exact definitions of the hypotheses are shown in Table 2. Exact values are presented in Table S4 (see Supporting Information)
| Spearman's rank correlation coefficients with GRC scalesa | 5. Mean change improvedb | 6. Mean change worsenedc | 7. Mean change improved > unchanged > worsened | Hypotheses confirmed | AUC | Responsive to change | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1. Similar (expected: high) | 2. Related #1 (expected: moderate) | 3. Related #2 (expected: moderate) | 4. Unrelated (expected: low) | |||||||
| SF‐36 GH | Low | Low | Low | Low | Negative | Positive | No | 14% | < 0·7 | No |
| SF‐36 BP | Low | Low | Low | Low | Positive | Positive | No | 29% | < 0·7 | No |
| SF‐36 PF | Low | Low | Low | Low | Positive | Negative | Yes | 57% | < 0·7 | No |
| SF‐36 SF | Low | Low | Low | Low | Negative | Negative | No | 29% | < 0·7 | No |
| SF‐36 MH | Low | Low | Low | Low | Positive | Negative | Yes | 57% | < 0·7 | No |
| SF‐36 RP | Low | Low | Low | Low | Positive | Positive | No | 29% | < 0·7 | No |
| SF‐36 RE | Low | Low | Low | Low | Positive | Positive | No | 29% | < 0·7 | No |
| SF‐36 PCS | Low | Low | Low | Low | Positive | Positive | No | 29% | < 0·7 | No |
| SF‐36 MCS | Low | Low | Low | Low | Positive | Negative | Yes | 57% | < 0·7 | No |
| SF‐36 sum | Low | Low | Low | Low | Positive | Negative | Yes | 57% | < 0·7 | No |
| Skindex S | Moderate | Low | Low | Low | Positive | Negative | Yes | 57% | < 0·7 | No |
| Skindex F | Low | Low | Low | Low | Negative | Positive | No | 14% | < 0·7 | No |
| Skindex E | Low | Low | Low | Low | Positive | Positive | No | 29% | < 0·7 | No |
| Skindex sum | Low | Low | Low | Low | Positive | Positive | No | 29% | < 0·7 | No |
Confirmed hypotheses are shown in bold. A subscale was considered responsive to change if ≥ 75% of the hypotheses were confirmed. GRC, global rating of change; AUC, area under the receiver operating characteristics curve; GH, general health; BP, bodily pain; PF, physical function; SF, social function; MH, mental health; RP, role physical; RE, role emotional; PCS, physical health component score; MCS, mental health component score; S, symptoms; F, functioning; E, emotions. aSimilar: correlation strength with the GRC scale measuring a similar construct as defined in Table 1. Related #1: correlation strength with the first GRC scale measuring a related, but dissimilar construct as defined in Table 1. Related #2: correlation strength with the second GRC scale measuring a related, but dissimilar construct as defined in Table 1. Unrelated: correlation strength with the GRC scale measuring an unrelated construct as defined in Table 1. Correlation was interpreted as high (> 0·5), moderate (0·3–0·5) or low (< 0·3). bThe mean change score of the patients indicating improvement on the associated GRC scale. cThe mean change score of the patients indicating worsening on the associated GRC scale.