Skip to main content
. 2020 May 26;26(34):7638–7646. doi: 10.1002/chem.202000417

Figure 3.

Figure 3

Conformational analyses of HIF‐1α812–826 sE816C‐R820C: a) 100 ns MD simulation of wt‐HIF‐1α812–826 peptide in the absence (top panel) and presence (bottom panel) of p300, b) MD simulations of the HIF‐1α812–826 oxE816C‐R820C peptide (panels to the right) in the absence (top panel) and presence (bottom panel) of p300, c) MD simulations of HIF‐1α812–826 sE816C‐R820C in isolation and in complex with p300 in the two dominant conformations adopted, d) MD snapshot of two stable p300 bound conformations of HIF‐1α812–826 sE816C‐R820C.