Fig. 4.

Subcellular distribution of the surface proteins identified in this study. Four hundred thirty-one surface proteins were classified into functional subgroups based on their main function as listed in the UniProt database entries (GO molecular function and/or GO biological process) into the following major functional groups: transporters, receptors, enzymes, extracellular matrix components, proteins involved in cell adhesion and cell junctions, and unclassified proteins. Data are based on labelling performed on chondrocytes obtained from two different horses (2 biological replicates). Note that some proteins appear in more than one category. Numbers in the pie chart represent the actual numbers of proteins in each subgroup