Table 2.

Summary statistics from tissue immunohistochemistry image analysis. The table shows the number of individuals and cells counted for each tissue region and subject group. The number of neurons or glial cells and RBM45 nuclear and cytoplasmic inclusions were counted as described in the Methods section. For each subject, a total of 8 fields per region (hippocampal dentate gyrus or lumbar spinal cord) were evaluated. FTLD-TDP = frontotemporal lobar degeneration with TDP-43 proteinopathy

Group	N	Total Cells	Mean Cells/ Field	SEM Cells/ Field	Mean Nuclear RBM45 Inclusions/Cell	SEM Nuclear RBM45 Inclusions/Cell	Mean Cytoplasmic RBM45 Inclusions/Cell	SEM Cytoplasmic RBM45 Inclusions/Cell
Dentate Gyrus Granule Cells
Control	10	4145	51.81	4.92	0.44	0.09	0	0
AD	5	1590	39.75	8.32	0.98	0.34	0.044	0.051
ALS	8	2943	45.98	5.98	1.49	0.27	0.048	0.055
FTLD-TDP	6	1962	40.92	5.81	2.38	0.23	0.109	0.072
Spinal Cord Glial Cells
Control	9	693	9.62	1.18	0.23	0.06	0	0
ALS	15	2689	22.35	1.74	1.04	0.18	0.11	0.47
Spinal Cord Motor Neurons
Control	9	308	4.29	0.53	0	0	0	0
ALS	15	351	2.91	0.42	0	0	0.15	0.14