Table 2.
Top 10 GO terms related to ROS enriched (FDR < 10−6) by trypsin
| Pattern | Number | GO ID | Term Type | Description | p-value* | FDRa |
|---|---|---|---|---|---|---|
| Upregulation | 8 | GO:0016701 | MF | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 2.01E-12 | 1.11E-08 |
| 25 | GO:0016491 | MF | oxidoreductase activity | 3.79E-11 | 1.05E-07 | |
| Downregulation | 6 | GO:0042744 | BP | hydrogen peroxide catabolic process | 7.85E-10 | 6.07E-07 |
| 6 | GO:0042743 | BP | hydrogen peroxide metabolic process | 8.80E-10 | 6.07E-07 | |
| 11 | GO:0004601 | MF | peroxidase activity | 4.05E-12 | 1.77E-08 | |
| 11 | GO:0016684 | MF | oxidoreductase activity, acting on peroxide as acceptor | 6.40E-12 | 1.77E-08 | |
| 11 | GO:0016209 | MF | antioxidant activity | 2.75E-11 | 5.07E-08 | |
| 5 | GO:0050664 | MF | oxidoreductase activity, acting on NAD(P) H, oxygen as acceptor | 5.88E-11 | 8.06E-08 | |
| 28 | GO:0016491 | MF | oxidoreductase activity | 7.30E-11 | 8.06E-08 | |
| 31 | GO:0003824 | MF | catalytic activity | 1.80E-10 | 1.65E-07 |
*p-values were calculated using Fisher’s test
aFDR corrections were calculated using the Benjamini-Hochberg procedure