Table 5.
Topological parameters of the ROS related genes, DERGs and Hub genes of the PPI subnetwork of H. undatus impacted by trypsin
| PPI subnetwork | y = βxα | R2 | Correlation | Clustering coefficient | Network centralization | Network density | Num. of nodes | Characteristic path length |
|---|---|---|---|---|---|---|---|---|
| ROS related genes network | ||||||||
| Total ROS | y = 137.73x-1.213 | 0.798 | 0.891 | 0.381 | 0.150 | 0.025 | 404 | 3.920 |
| Upregulated ROS | y = 52.493x-0.889 | 0.765 | 0.853 | 0.413 | 0.286 | 0.052 | 278 | 2.839 |
| Downregulated ROS | y = 60.805x-0.931 | 0.762 | 0.733 | 0.353 | 0.299 | 0.048 | 288 | 2.748 |
| DERGs of ROS subnetwork | ||||||||
| Total DERGs | y = 7.431x-0.521 | 0.412 | 0.582 | 0.361 | 0.395 | 0.144 | 60 | 2.397 |
| Upregulated DERGs | y = 4.697x-0.532 | 0.422 | 0.807 | 0.354 | 0.355 | 0.186 | 30 | 2.448 |
| Downregulated DERGs | y = 3.289x-0.026 | 0.001 | −0.021 | 0.239 | 0.222 | 0.164 | 28 | 2.437 |
| Hubs subnetwork | ||||||||
| Total 10 hubs | y = 0.688 × 0.468 | 0.268 | 0.499 | 0.849 | 0.333 | 0.733 | 10 | 1.267 |