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. 2020 Jun 26;20:202. doi: 10.1186/s12876-020-01351-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Histological features of pancreatic undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) under 100X (H&E, a). UC-OGC associated with poorly differentiated ductal adenocarcinoma component under 100X (H&E, b). The UC-OGC composed of anaplastic carcinoma and intermixed with pleomorphic neoplastic mononuclear cells and multinucleated osteoclast-like giant cells under 200X (H&E, c and d). Osteoclast-like giant cells of the tumor were stained positive for CD68 (IHC, e). Staining was positive for CK7 diffusely in the PDAC component of the tumor (IHC, f)