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. 2020 Feb 25;21(10):1461–1472. doi: 10.1002/cbic.201900751

Figure 4.

Figure 4

Extracted ion chromatograms of A) non‐deuterated (D0) and B) deuterated (D12) hydroxy metabolites of mefenamic acid, formed after incubations of P450 BM3 M11 with an equimolar mixture of deuterated (D12/13) and nondeuterated mefenamic acid (total concentration 750 μm), respectively.