Table 2.

Demographic and Pathologic Data of Main TDP‐43 Histotypes

	TDP‐A donors	TDP‐B donors	TDP‐C donors	TDP‐E donors
N	17	14	13	7
Gender, M:F	7:10	6:8	6:7	5:2
Age at onset, mean ± SD	60.82 ± 8.58	57.29 ± 15.25	58.39 ± 5.58	62.43 ± 6.32
Age at diagnosis, mean ± SD	62.59 ± 8.50	60.50 ± 13.88	61.85 ± 4.12	64.57 ± 4.83
Age at death, mean ± SD	67.71 ± 8.36	64.64 ± 12.73	68.69 ± 3.40	66.14 ± 4.34
Disease duration, yrs; mean ± SD	6.88 ± 3.79	7.36 ± 5.00	10.31 ± 3.40	3.71 ± 3.40
Time to diagnosis, yrs; mean ± SD	1.77 ± 2.25	3.21 ± 3.56	3.46 ± 3.53	2.14 ± 3.53
Time to dependency in ADL, yrs; mean ± SD	3.06 ± 2.91	4.54 ± 3.78	5.92 ± 2.84	2.86 ± 3.67
Brain weight, gr; mean ± SD	1026.18 ± 153.51	1060.29 ± 218.91	1039.15 ± 136.76	1178 ± 98.91
Thal stage, median; IQR	0.5 (0–2)	1 (0–3)	1 (0.5–2)	2 (1–3)
Braak stage for tau, median; IQR	2 (0–3.75)	2 (1–2.25)	1 (0.5–2)	1 (0–2)
Braak stage for Lewy body, median; IQR	0 (0–0)	0 (0–0)	0 (0–0)	0 (0–0)

Values are expressed as mean ± SD or median ± IQR.

ADL = activities of daily living; IQR = interquartile range; TDP = TAR DNA‐binding protein.