Table 3.

Variable associated with organ/space surgical site infection (SSI)

SSI	Univariate		Multivariate
	OR (95% CI)	p value	OR (95% CI)	p value
Age in years, mean ± SD	1.002 (0.96–1.03)	0.891
BMI, median (range)	1.104 (1.01–1.20)	0.024	1.107 (0.99–1.22)	0.057
Sex, n (%)
Male	1
Female	1.507 (0.71–3.18)	0.281
Comorbidities, n (%)
Diabetes mellitus	0.284 (0.09–0.84)	0.024
Hypertension	1.263 (0.59–2.67)	0.542
Dyslipidemia	0.765 (0.32–1.80)	0.541
Renal insufficiency	1.453 (0.15–13.42)	0.742
ASA class, n (%), n = 242
I	1
II	0.144 (0.02–0.81)	0.029
III	0.169 (0.03–0.90)	0.038
IV	0.333 (0.03–3.20)	0.341
Smoking, n (%)	0.531 (0.20–1.35)	0.187
Previous biliary intervention, n (%)	1.864 (0.79–4.35)	0.150
WBC, mean ± SD	0.933 (0.80–1.08)	0.369
Platelet ×103, median (range)	0.741 (0.50–1.08)	0.125
Hemoglobin in g/dL, median (range)	0.997 (0.85–1.15)	0.970
BUN in mg/dL, median (range)	1.001 (0.94–1.06)	0.967
Creatinine in mg/dL, median (range)	0.734 (0.25–2.07)	0.561
Total bilirubin in mg/d/L, median (range)	0.981 (0.92–1.04)	0.538
Albumin in g/L, mean ± SD	0.951 (0.89–1.01)	0.128
Preoperative cholangitis, n(%)	12.193 (1.07–138.54)	0.044	10.722 (2.31–49.75)	0.002
Operative time in min, median (range)	1.126 (0.83–1.51)	0.428
Blood loss in ml, median (range)	1.264 (1.01–1.59)	0.046
Complications, n (%)
Pancreatic fistula
No	1		1
Yes	8.399 (3.10–22.71)	0.000	6.531 (2.30–18.51)	0.000
Bile leakage	2.482 (0.73–8.44)	0.145
Delayed gastric emptying	1.733 (0.53–5.63)	0.360
Chyle leakage	1.978 (0.38–10.24)	0.416
Diagnosis, n (%)
Benign	1
Malignant	0.952 (0.41–2.18)	0.908

SSI Surgical site infection, OR Odds ratio, CI Confidence interval, BMI Body mass index, ASA American Society of Anesthesiologists, WBC White blood cell count, BUN Blood urea nitrogen