Table 6.
Summarization of recent studies of risks of surgical site infection after pancreaticoduodenectomy
| Author (year) | Type of study | No. of patients | Incidence of SSI (%) | Percent of malignancy (%) | Risk factors of surgical site infection |
|---|---|---|---|---|---|
| Poluk K. E (2016) [37] | Single center retrospective | 679 | 17.2 | – |
Pre-operative biliary drainage, Neoadjuvant chemotherapy |
| Zhang L (2016) [9] | Single center retrospective | 212 | 29a | 80 |
Pancreatic fistula, Blood transfusion |
| Barreto S. G (2015) [7] | Single center retrospective | 277 | 35 | 81 |
Pre-operative biliary stent insertion, Non-diabetic endocrine co-morbidity. |
| De Pastena M (2017) [17] | Single center retrospective | 893 | 45.8† | – | Pre-operative biliary drainage |
| Sugiura T (2012) [8] | Single center retrospective | 408 | 51 | 90 |
Long operative time, High Body Mass Index, Pancreatic fistula, Semi-close suction drain, Main pancreatic duct < 3 mm, Abdominal wall fat thickness > 10 mm. |
| Burkhart R. A (2017) [2] | Single center retrospective | 394 | 19.8 | 71.1 | Pre-operative biliary drainage, neoadjuvant therapy, prior abdominal surgery |
| Shinkawa H (2018) [10] | Single center retrospective | 106 | 14.2 | – |
Nutritional risk index, Pancreatic fistula |
| Gavazzi F (2016) [35] |
Single center retrospective |
180 | 52.3 | 86 |
Pre-operative biliary stent, Cardiac disease, BMI > 25 mg/m2 |
| Okano K (2015) [30] |
Multi center retrospective |
4147 | 27.1 | 90 |
Male sex, age 70 years or more, Body mass index at least 25 kg/m2, Other previous malignancy, Liver disease, Bile contamination, Duration of surgery 7 h or longer, Intraoperative blood transfusion, Soft pancreas |
a Overall infectious complication
- Not stated