Table 4.
Adverse Events of Grade ≥3 During the Observation Period.
All, n = 94 | Child-Pugh class A, n = 62 | Child-Pugh class B, n = 32 | ||||
---|---|---|---|---|---|---|
TACL-ECF, n = 49 | Sorafenib group, n = 45 | TACL-ECF, n = 33 | Sorafenib group, n = 29 | TACL-ECF, n = 16 | Sorafenib group, n = 16 | |
Nausea/vomiting | 1 (2.0%) | 1 (2.2%) | 0 (0%) | 0 (0%) | 1 (6.3%) | 1 (6.3%) |
Fatigue | 1 (2.0%) | 1 (2.2%) | 0 (0%) | 1 (3.4%) | 1 (6.3%) | 0 (0%) |
Hand-foot syndrome | 0 (0%) | 4 (8.9%) | 0 (0%) | 3 (10.3%) | 0 (0%) | 1 (6.3%) |
Elevated aspartate aminotransferase | 3 (6.1%) | 6 (13.3%) | 1 (3.0%) | 2 (6.9%) | 2 (12.5%) | 4 (25.0%) |
Bone marrow suppression | 1 (2.0%) | 0 (0%) | 1 (3.0%) | 0 (0%) | 0 (0%) | 0 (0%) |
Hepatic encephalopathy | 0 (0%) | 1 (2.2%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (6.3%) |
Variceal bleed | 0 (0%) | 2 (4.4%) | 0 (0%) | 1 (3.4%) | 0 (0%) | 1 (6.3%) |
Pulmonary thromboembolism | 0 (0%) | 1 (2.2%) | 0 (0%) | 1 (3.4%) | 0 (0%) | 0 (0%) |