Table 2.

Differences in Diffusion Tensor Imaging Scalars Between 31 Neonates With Perinatal HIE Following Therapeutic Hypothermia and 10 Clinical Controls.^a

	FA			MD (× 10−3 mm/s2)			AD (× 10−3 mm/s2)			RD (× 10−3 mm/s2)
Regions of interest	HIE	Control	Significance	HIE	Control	Sig.	HIE	Control	Sig.	HIE	Control	Sig.
Right putamen	0.129 (0.031)	0.150 (0.027)	.05*	1.114 (0.068)	1.113 (0.052)	.97	1.260 (0.073)	1.270 (0.57)	.72	1.041 (0.071)	1.019 (0.044)	.28
Left putamen	0.134 (0.026)	0.156 (0.027)	.03*	1.108 (0.064)	1.097 (0.066)	.66	1.256 (0.065)	1.247 (0.059)	.73	1.034 (0.068)	1.002 (0.058)	.20
Thalamus	0.168 (0.031)	0.180 (0.026)	.25	1.032 (0.072)	1.046 (0.070)	.62	1.199 (0.076)	1.213 (0.054)	.58	0.948 (0.075)	0.954 (0.072)	.82
Right PLIC	0.466 (0.054)	0.476 (0.040)	.59	1.056 (0.076)	1.044 (0.056)	.65	1.659 (0.089)	1.654 (0.092)	.88	0.754 (0.093)	0.739 (0.059)	.62
Left PLIC	0.470 (0.061)	0.467 (0.036)	.88	1.043 (0.080)	1.033 (0.062)	.73	1.643 (0.088)	1.623 (0.087)	.53	0.742 (0.104)	0.738 (0.062)	.90
Genu CC	0.541 (0.085)	0.544 (0.090)	.92	1.285 (0.130)	1.228 (0.081)	.27	2.176 (0.207)	2.120 (0.112)	.42	0.840 (0.146)	0.783 (0.117)	.27
Splenium CC	0.608 (0.078)	0.649 (0.033)	.02*	1.198 (0.131)	1.145 (0.059)	.23	2.168 (0.166)	2.133 (0.054)	.31	0.713 (0.147)	0.617 (0.047)	.00**
Anterior CSO	0.152 (0.290)	0.199 (0.047)	.05*	1.517 (0.202)	1.440 (0.148)	.28	1.747 (0.194)	1.704 (0.130)	.52	1.402 (0.220)	1.286 (0.170)	.13
Posterior CSO	0.154 (0.029)	0.204 (0.051)	.01*	1.608 (0.139)	1.471 (0.166)	.01*	1.859 (0.135)	1.772 (0.155)	.1	1.483 (0.145)	1.316 (0.188)	.01**

Abbreviations: AD, axial diffusivity; CC, corpus callosum; CSO, centrum semiovale; FA, fractional anisotropy; HIE, hypoxic-ischemic encephalopathy; MD, mean diffusivity; PLIC, posterior limb of the internal capsule; RD, radial diffusivity; Sig., significance.

^aData presented In the HIE and control columns include the mean (standard deviation). Boldface Indicates statistical significance.

^*P < .05

^**P < .01.