Fig. 2.

Technologies promoting cell-mediated antigen trafficking to lymph nodes. (A) TEM image of Alhydrogel adjuvant (Adapted from [64]). (B) Cryo-TEM images of an oil-in-water emulsion adjuvant similar to the licensed adjuvant MD59 (Adapted from [144]). (C) Peptide sequence Q11 forming beta-sheet-enriched nanofibers in vitro with and without N-terminal OVA peptide (Adapted from [74]). (D) PLGA macroporous implantable scaffold used as a vaccine platform that can be loaded with cancer cell lysates or peptides, CpG adjuvant, and GM-CSF to promote DC recruitment, antigen loading, and activation (Adapted from [83]). Scale bar: 200 microns.