Figure 4.

Inhibitory effects of drugs on cell proliferation in vitro and in vivo. (A) Cell Counting Kit-8 (CCK-8) assay. The x-axis represents drug concentration (0, 10, 30, and 60 μg/ml), and the y-axis represents cell activity, as determined using the CCK-8 assay. Results are expressed as the mean ± SEM (n = 3). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001. (B) Tumor volume. The horizontal axis represents days and the vertical axis represents tumor volume (mm³). (C) Tumor size. (D) Tumor weights. The vertical axis represents tumor weights (g). Results are expressed as the mean ± SEM (n = 5). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.