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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Cancer Causes Control. 2020 May 11;31(7):683–689. doi: 10.1007/s10552-020-01313-0

Table 3.

Factors associated with overall survival of incident colorectal cancers in National Cancer Database diagnosed during 2010–2014 by tumor deposit status

HR 95% CI Pa
Tumor-deposits absent in resected tumorb
 MSI (Unstable/High vs Stable/Low) 0.89 (0.79 – 0.997) 0.044
 KRAS (Mutated vs Wild type) 1.24 (1.14 – 1.35) <0.001
Tumor-deposits present in resected tumorc
 MSI (Unstable/High vs Stable/Low) 1.12 (0.97 – 1.30) 0.124
 KRAS (Mutated vs Wild type) 1.20 (1.07 – 1.33) 0.001
No tumor resectiond
 MSI (Unstable/High vs Stable/Low) 0.51 (0.24 – 1.08) 0.078
 KRAS (Mutated vs Wild type) 2.07 (1.33 – 3.22) 0.001

MSI, microsatellite instability.

a

P of multivariate Cox regression analyses adjusted for age, tumor grade, pathologic stage, Charlson-Deyo score, chemotherapy status, radiotherapy status and race.

b

Age, pathologic stage and chemotherapy status included as time-varying covariates.

c

Tumor grade and chemotherapy status included as time-varying covariates.

d

Chemotherapy status included as time-varying covariate.