Table 2.
The characteristics of the patients with confirmed coronavirus disease 2019 who were on secukinumab therapy
| Article | Age/sex | Disease | Duration on secukinumab therapy | Medical history | Presenting COVID-19 symptoms | Treatment | Outcome |
|---|---|---|---|---|---|---|---|
| Favalli [11] | 68/female | PsA | NR | NR | NR |
Not hospitalized Treatment details: NR |
Managed at home with no any respiratory complication |
| Di Lernia [24] | 73/female | PsA | 12–13 months |
Hypertension Tachycardia Osteoporosis Fractures Hyperuricemia |
Fever Sore throat Mild cough |
HQ regimen (800 mg/day for 2 days, followed by 400 mg/day for 5 days) | Recovered, 2 negative RT-PCR tests |
| Sharmeen [25] | 78/male | AS | 16 months |
Medications: Amlodipine Hydrochlorothiazide Losartan Nortriptyline Levothyroxine Rosuvastatin Tamsulosin |
Fever Severe dry cough Fatigue Myalgia Shortness of breath Frontal headache Lightheadedness |
Hospitalized HQ and azithromycin (5 days) Mechanical ventilation |
Remained intubated with mechanical ventilation |
| Haberman [26] | 51/male | PsA | NR |
Hypertension BMI > 35 |
Fever Cough Shortness of breath |
Hospitalized HQ and azithromycin |
Discharged at day 3 |
| Other cases with confirmed COVID-19 (n = 3) did not require hospitalization | |||||||
PsA psoriatic arthritis, COVID-19 coronavirus disease 2019, RT-PCR reverse transcription-polymerase chain reaction test, AS ankylosing spondylitis, NR not reported, BMI body mass index