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. 2020 Jun 26;15(6):e0235419. doi: 10.1371/journal.pone.0235419

Table 3. Association between physical exercise and moderate to severe chronic pain in male and female university and college and university students.

ICD-11 moderate to severe chronic pain
Unadjusted model Adjusted model§ Fully adjusted model#
n (%) OR 95% CI OR 95% CI OR 95% CI
Women
Physical exercise (frequency)
Never/less than once a week 858 (23.2) 1.00 1.00 1.00
Once a week 801 (19.8) 0.84 (0.74–0.94) 0.89 (0.79–0.99) 0.91 (0.81–1.03)
2–3 times per week 2124 (18.8) 0.79 (0.71–0.87) 0.85 (0.77–0.94) 0.90 (0.81–0.99)
Almost every day 918 (16.6) 0.67 (0.60–0.75) 0.74 (0.67–0.83) 0.79 (0.70–0.88)
Physical exercise (intensity)
I take it easy without breaking into a sweat or losing my breath 1037 (23.0) 1.00 1.00 1.00
I push myself so hard that I lose my breath and break into a sweat 3043 (17.8) 0.74 (0.68–0.80) 0.76 (0.69–0.82) 0.79 (0.72–0.86)
I push myself to near-exhaustion 413 (21.1) 0.90 (0.79–1.03) 0.91 (0.79–1.04) 0.94 (0.82–1.08)
Physical exercise (duration)
Less than 30 minutes 634 (23.0) 1.00 1.00 1.00
30 minutes to 1 hour 2419 (18.0) 0.74 (0.66–0.82) 0.77 (0.69–0.86) 0.80 (0.72–0.89)
More than 1 hour 1440 (19.5) 0.81 (0.72–0.90) 0.85 (0.76–0.95) 0.89 (0.79–0.99)
Men
Physical exercise (frequency)
Never/less than once a week 227 (9.8) 1.00 1.00 1.00
Once a week 117 (6.8) 0.65 (0.51–0.83) 0.70 (0.55–0.89) 0.73 (0.57–0.93)
2–3 times per week 284 (6.0) 0.57 (0.47–0.69) 0.61 (0.50–0.74) 0.65 (0.53–0.78)
Almost every day 220 (6.9) 0.67 (0.55–0.82) 0.74 (0.60–0.81) 0.79 (0.65–0.98)
Physical exercise (intensity)
I take it easy without breaking into a sweat or losing my breath 141 (8.6) 1.00 1.00 1.00
I push myself so hard that I lose my breath and break into a sweat 508 (6.6) 0.72 (0.59–0.88) 0.77 (0.62–0.94) 0.80 (0.65–0.98)
I push myself to near-exhaustion 133 (7.0) 0.76 (0.59–0.98) 0.79 (0.61–1.03) 0.83 (0.64–1.08)
Physical exercise (duration)
Less than 30 minutes 105 (8.8) 1.00 1.00 1.00
30 minutes to 1 hour 319 (6.9) 0.75 (0.59–0.95) 0.75 (0.59–0.86) 0.79 (0.62–1.00)
More than 1 hour 360 (6.6) 0.70 (0.56–0.89) 0.72 (0.56–0.91) 0.76 (0.60–0.97)

§ Adjusted for socio demographics, body-mass index, alcohol use and problems and sleep duration

# Additional adjustment for self-reported depression