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. 2020 Jun 26;15(6):e0235230. doi: 10.1371/journal.pone.0235230

Table 3. Subgroup analysis of multivariate Cox proportional hazard ratios for PMTR according to the history of open-heart surgery.

No open-heart surgery (n = 358) Open-heart surgery (n = 71)
HR (95% CI) P value HR (95% CI) P value
Age 1.03 (0.98–1.05) 0.395 1.07 (0.98–1.05) 0.045
Male sex 0.84 (0.34–2.07) 0.698 0.61 (0.34–2.07) 0.529
Atrial fibrillation 1.91 (0.79–4.62) 0.151 3.24 (0.87–12.06) 0.080
V pacing percentage 1.00 (0.99–1.01) 0.885 1.00 (0.98–1.02) 0.948
LVEF 0.99 (0.95–1.04) 0.827 1.03 (0.95–1.04) 0.349
LA volume index 0.99 (0.96–1.01) 0.313 0.99 (0.96–1.01) 0.617
RVEDA 0.92 (0.83–1.02) 0.101 1.02 (0.84–1.24) 0.832
RVFAC 0.99 (0.95–1.04) 0.717 1.01 (0.94–1.09) 0.840
TVAD/BSA 1.12 (0.96–1.30) 0.158 1.28 (0.98–1.65) 0.065
RVSP 1.01 (0.97–1.06) 0.554 1.02 (0.95–1.10) 0.557
TR
    No Ref Ref Ref
    Grade 1 0.16 (0.03–0.77) 0.022 1.60 (0.33–7.71) 0.559
    Grade 2 0.01 (0.08-inf) 0.997 1.54 (0.16–15.12) 0.712

HR, hazard ratio; CI, confidence interval; LVEF, left ventricular ejection fraction; LA, left atrium; RVEDA, right ventricular end-diastole area; RVESA, right ventricular end-systole area; TVAD, tricuspid valve annular diameter; BSA, body surface area’ RVSP, right ventricular systolic pressure.