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. 2020 Jun 26;5(48):eabd2071. doi: 10.1126/sciimmunol.abd2071

Fig. 5. SARS-CoV-2-specific cytokine production in COVID-19 ARDS patients.

Fig. 5

(A-J) Antigen-specific production of cytokines measured in cell culture supernatants from PBMC obtained 14 days post ICU admission stimulated (20 hours) with MP_S. Two left panels show quantities obtained with the vehicle control (DMSO) and specific stimulation (MP) for HC and COVID-19 patients. The third panel shows the quantity corrected by subtracting the background present in the DMSO stimulation to allow comparison of both groups. Panels show individual values for n=10 patients versus n=10 HC, as well as the geometric mean. Asterisk denotes a significant difference. HC = healthy control. Additional cytokines (IL-4, IL-17F and IL-21) are shown in Fig. S2. Symbol shapes of COVID-19 patients are identical between panels, and refer back to Fig. 1.