Table 3.
Effect of Hydromethanolic Seed Extract of D. stramonium in Normoglycemic Mice
Fasting BGL (mg/dL) | |||||
---|---|---|---|---|---|
Groups | 0 hour | 1 hour | 2 hours | 4 hours | 6 hours |
10 mL/kg NC | 90.46±0.31 | 88.29±0.75 | 80.52±0.68 | 75.82±1.71 | 75.06±2.03 |
5 mg/kg GB | 89.28±1.02 | 72.82±0.91 | 66.79±1.06a,**,b,* | 60.39±2.29a,**,b,* | 56.45±2.09a,**,b,* |
100 mg/kg SE | 90.53±1.75 | 87.21±0.42 | 79.58±0.74c,* | 74.83±1.73c,* | 74.09±0.39c,* |
200 mg/kg SE | 89.53±0.45 | 86.45±1.90 | 77.88±1.30 | 73.97±1.17 | 73.56±2.03 |
400 mg/kg SE | 90.06±1.64 | 85.51±0.46 | 77.62±1.29 | 72.88±1.25 | 72.11±2.69 |
Notes: Each data describes as mean±standard error of the mean, n=6; acompared to negative control; bto 100 mg/kg; cto 5 mg/kg GB; *P<0.05; **P<0.001.
Abbreviations: BGL, blood glucose level; GB, glibenclamide; NC, negative control; SE, seed extract.