Table 4.
Antihyperglycemic Effects of 80% Methanolic Seed Extract of D. stramonium in Diabetic Mice
Group | Fasting BGL (mg/dL) | ||
---|---|---|---|
Day 0 | Day 7 | Day 14 | |
10 mL/kg NC | 254.62±1.05 | 266.00±1.73 | 268.94±0.49 |
5 mg/kg GB | 255.46±0.34 | 243.22±0.42a,** | 240.18±1.63a,** |
100 mg/kg SE | 256.06±1.27 | 255.06±0.57a,* | 250.22±0.29a,* |
200 mg/kg SE | 255.44±0.88 | 249.17±1.06a,* | 248.55±1.06a,* |
400 mg/kg SE | 255.89±0.92 | 246.45±0.51a,* | 247.17±0.25a,* |
Notes: Each data described as mean±standard error of the mean, n=6; acompared to negative control; *P<0.01; **P<0.001.
Abbreviations: BGL, blood glucose level; GB, glibenclamide; NC, negative control; SE, seed extract.