Table 2.
Comparison of the main features of miRNet (versions 1.0–2.0) with other web-based or web-enabled tools. Symbols used for feature evaluations with ‘√’ for present, ‘−’ for absent, and ‘+’ for a more quantitative assessment (more ‘+’ indicate better support)
| miRNet | ||||||
|---|---|---|---|---|---|---|
| Tool name | 2.0 | 1.0 | miRTargetLink | MIENTURNET | Arena-Idb | starBase |
| Data input and processing | ||||||
| Species # | 11 | 8 | 1 | 6 | 1 | 23 |
| Target genes | ||||||
| Experimental | +++ | ++ | ++ | + | ++ | +++ |
| Predicted | √ | √ | √ | √ | √ | √ |
| Other targets & associations | ||||||
| miR-SNP | √ | − | − | − | − | − |
| TF | √ | − | − | − | − | − |
| ncRNA | +++ | + | − | − | + | ++++ |
| xeno-miRNA | √ | − | − | − | − | − |
| Disease | +++ | ++ | − | − | ++ | ++ |
| Epigenetic modifier | √ | √ | − | − | − | − |
| Small molecule | √ | √ | − | − | − | − |
| Expression profiling | √ | √ | − | − | − | − |
| Enrichment analysis | ||||||
| Hypergeometric tests | √ | √ | √ | √ | − | √ |
| Empirical sampling | √ | √ | − | − | − | − |
| miR-set enrichment | √ | − | − | − | − | − |
| Network visual analytics | ||||||
| Multiple query types | √ | − | − | − | − | − |
| Integration with PPI network | √ | − | − | − | − | − |
| Multipartite network visualization | √ | − | − | − | − | − |
| Subnetwork extraction | √ | − | − | − | − | − |
URL links:
miRTargetLink: https://ccb-web.cs.uni-saarland.de/mirtargetlink/
MIENTURNET: http://userver.bio.uniroma1.it/apps/mienturnet/
starBase: http://starbase.sysu.edu.cn/index.php