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. 2020 May 13;48(W1):W132–W139. doi: 10.1093/nar/gkaa361

Figure 1.

Figure 1.

MISCAST architecture, main modules, and data flow. (A) Online resources used for collecting missense variants, gene symbols, protein sequences and structures. (B) Databases searched to aggregate gene- and residue-wise biological context annotations. (C) MISCAST development using Shiny R package and deployment using Google Cloud services. (D) Three main visualization schemes of MISCAST. Missense variants and protein features are displayed in 1D, 2D and concurrent 1D </> 3D views.