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. 2020 Jun 26;15(6):e0231563. doi: 10.1371/journal.pone.0231563

Table 3. Association between anxiety and depression and functional difficulties in hearing*.

People with hearing functional difficulties (a lot or cannot do) People without hearing functional difficulties (no difficulty/some difficulty) OR (95% CI) adjusted for age and sex P-value
Nepal N = 48 N = 3,934 N = 3,982
Anxiety
    • Severe 10.4% 1.1% 9.6 (3.5, 26.6) <0.001
    • Moderate 10.4% 4.3% 2.4 (0.9, 6.2) 0.08
    • Mild/None 79.2% 94.6% Baseline
Depression
    • Severe 8.5% 0.8% 11.7 (3.8, 36.5) <0.001
    • Moderate 21.3% 4.7% 4.9 (2.3, 10.2) <0.001
    • Mild/None 70.2% 94.5% Baseline
Guatemala n = 120 n = 7,481 n = 7,600
Anxiety
    • Severe 25.0% 5.8% 4.9 (3.1, 7.8) <0.001
    • Moderate 22.5% 21.2% 1.5 (0.9, 2.3) 0.11
    • Mild/None 52.5% 73.0% Baseline
Depression
    • Severe 20.0% 2.8% 6.3 (3.8, 10.4), <0.001
    • Moderate 14.2% 13.0% 1.3 (0.7, 2.2) 0.38
    • Mild/None 65.8% 84.1% Baseline
India n = 85 n = 2,247 n = 2,332
Anxiety
    • Severe 15.3% 7.5% 1.7 (0.9, 3.2) 0.12
    • Moderate 21.2% 19.5% 1.0 (0.6, 1.7) 0.90
    • Mild/None 63.5% 73.0% Baseline
Depression
    • Severe 13.4% 5.8% 1.9 (0.9, 3.8) 0.07
    • Moderate 18.3% 16.1% 1.0 (0.6, 1.8) 0.97
    • Mild/None 68.3% 78.1% Baseline
Cameroon n = 32 n = 1,567 n = 1,599
Anxiety
    • Severe 9.4% 5.8% 1.4 (0.4, 5.0) 0.56
    • Moderate 25.0% 25.7% 1.1 (0.5, 2.5) 0.84
    • Mild/None 65.6% 68.5% Baseline
Depression
    • Severe 6.5% 4.8% 0.9 (0.2, 4.2) 0.94
    • Moderate 16.1% 19.4% 0.8 (0.3–2.2) 0.71
    • Mild/None 77.4% 75.8% Baseline
Maldives n = 36 n = 3,664 n = 3,700
Anxiety
    • Severe 22.2% 8.1% 2.8 (1.2–6.5) 0.02
    • Moderate 2.8% 5.7% 0.5 (0.1–4.2) 0.56
    • Mild/None 75.0% 86.3% Baseline
Depression
    • Severe 13.9% 6.5% 2.1 (0.8–5.7) 0.15
    • Moderate 5.6% 4.4% 1.7 (0.4–7.5) 0.50
    • Mild/None 80.6% 89.1% Baseline

* There were some missing data for depression variables: 3–5 people within Nepal, Guatemala, and India across cases and controls, and 1 case and 49 controls in Cameroon.