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. 2020 Jun 26;15(6):e0231563. doi: 10.1371/journal.pone.0231563

Table 5. Association between anxiety and depression and functional difficulties in mobility.

People with mobility functional difficulties (a lot or cannot do) People without mobility functional difficulties (no difficulty/ some difficulty) OR (95% CI) adjusted for age and sex p-value
Nepal n = 79 n = 3,903 n = 3,982
Anxiety
    • Severe 10.1% 1.0% 12.6 (5.4, 29.5) <0.001
    • Moderate 21.5% 4.1% 7.2 (4.0, 13.1) <0.001
    • Mild/None 68.4% 95.0% Baseline
Depression
    • Severe 7.6% 0.7% 14.2 (5.4, 37.1) <0.001
    • Moderate 29.1% 4.4% 9.6 (5.5, 16.4) <0.001
    • Mild/None 63.3% 94.8% Baseline
Guatemala n = 214 n = 7,387 n = 7,600
Anxiety
    • Severe 34.1% 5.3% 10.4 (7.3, 14.7) <0.001
    • Moderate 24.3% 21.1% 2.0 (1.4, 2.9) <0.001
    • Mild/None 41.6% 73.6% Baseline
Depression
    • Severe 25.7% 2.5% 13.9 (9.4, 20.6) <0.001
    • Moderate 22.4% 12.8% 2.7 (1.9, 3.8) <0.001
    • Mild/None 51.9% 84.8% Baseline
India n = 111 n = 2,221 n = 2,332
Anxiety
    • Severe 22.5% 7.0% 4.0 (2.3, 6.9) <0.001
    • Moderate 28.8% 19.1% 1.8 (1.1, 2.9) 0.02
    • Mild/None 48.7% 73.8% Baseline
Depression
    • Severe 22.5% 5.2% 5.4 (3.1, 9.4) <0.001
    • Moderate 23.4% 15.8% 1.7 (1.0, 2.8) 0.04
    • Mild/None 54.1% 79.0% Baseline
Cameroon n = 87 n = 1,505 n = 1,592
Anxiety
    • Severe 17.2% 5.2% 4.4 (2.3, 8.7) <0.001
    • Moderate 32.2% 25.2% 1.9 (1.2, 3.2) 0.01
    • Mild/None 50.6% 69.6% Baseline
Depression
    • Severe 19.0% 5.5% 4.5 (2.3, 8.8) <0.001
    • Moderate 27.9% 17.4% 2.5 (1.4, 4.3) 0.001
    • Mild/None 53.2% 77.2% Baseline
Maldives n = 166 n = 3,534 n = 3,700
Anxiety
    • Severe 25.9% 7.4% 5.2 (3.4–7.9) <0.001
    • Moderate 7.2% 5.6% 2.0 (1.0–3.8) 0.05
    • Mild/None 66.9% 87.1% Baseline
Depression
    • Severe 25.3% 5.7% 7.7 (4.9–12.1) <0.001
    • Moderate 6.6% 4.3% 3.2 (1.6–6.6) 0.001
    • Mild/None 68.1% 90.0% Baseline

* There were some missing data for depression variables: 3–6 people within Nepal, Guatemala, and India across cases and controls, and 8 cases and 41 controls in Cameroon.