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Top 15 proteins based on the topological properties in PPI network of 120 dysregulated genes, and arranged on the basis of the decreasing degree of connectivity value.
| Hub genes | Degree | Betweenness centrality |
|---|---|---|
| STAT1 | 55 | 0.247 |
| IRF7 | 48 | 0.041 |
| IFIH1 | 45 | 0.044 |
| MX1 | 45 | 0.013 |
| ISG15 | 44 | 0.051 |
| IFIT3 | 44 | 0.028 |
| OAS2 | 44 | 0.012 |
| DDX58 | 43 | 0.015 |
| IRF9 | 42 | 0.019 |
| IFIT1 | 42 | 0.007 |
| OAS1 | 42 | 0.006 |
| OAS3 | 42 | 0.006 |
| DDX60 | 41 | 0.027 |
| OASL | 41 | 0.006 |
| IFIT2 | 41 | 0.003 |
