Table 6.
FACIT-F: responsiveness and ability to detect change in SLE (within-group)
| Reference | Anchor (clinical severity measure) |
Findings | ||
| SRI responder mean | SRI non-responder mean | P value | ||
| Furie et al35 | SRI responder | 5.2 | 3.0 | <0.001 |
| Improved | Unchanged | Worsened | ||
| Mean (SD), ES, p value | Mean (SD), ES, p value | Mean (SD), ES, p value | ||
| Lai et al52 | BILAG musculoskeletal change | 7.1 (10.7), 0.66, <0.001 |
3.3 (11.0), 0.30, 0.004 |
2.5 (11.6), 0.22, 0.617 |
| BILAG general change | 8.2 (11.9), 0.69, <0.001 |
4.2 (10.2), 0.41, <0.001 |
0.0 (9.1), 0.00, 1.00 |
|
| Patient global assessment of change | 10.5 (12.9), 0.82, <0.001 |
3.1 (7.8), 0.40, <0.001 |
−3.6 (6.7), –0.53, p<0.016 | |
BILAG, British Isles Lupus Assessment Group; ES, effect size; FACIT-F, Functional Assessment of Chronic Illness Therapy-Fatigue Scale; SRI, SLE Responder Index.