TABLE 3.
Glucose values (mmol/L) in fasting state, and 60 and 120 min into OGTT at week 14–20 and at week 27–30 in the probiotic and placebo group. Furthermore, the number of women with a diagnosis of GDM (IADPSG criteria) as well as AUC values for OGTT in the Vivomixx® and placebo group are given
| OGTT glucose values, | Probiotic (n = 25) | Placebo (n = 25) | Probiotic (n = 25) | Placebo (n = 24) | ||
|---|---|---|---|---|---|---|
| mmol/L [median (IQL)] | Week (14–20) | Week (14–20) | P value | Week 27–30 | Week 27–30 | P value |
| 0 | 4.3 (4.1: 4.6) | 4.4 (4.1: 4.6) | 0.54 | 4.3 (3.9: 4.9) | 4.3 (4.0: 4.5) | 0.85 |
| 60 | 6.9 (6.2: 8.0) | 6.8 (6.3: 8.4) | 0.63 | 7.3 (6.5: 8.4) | 7.3 (6.8: 8.7) | 0.32 |
| 120 | 6.2 (5.4: 6.8) | 5.9 (5.4: 6.9) | 0.41 | 6.3 (5.9: 7.1) | 6.0 (5.3: 6.9) | 0.41 |
| GDM diagnosis, n (%) | 2 (8%) | 2 (8%) | 1.00 | 4 (16%) | 2 (8%) | 0.67 |
| OGTT AUC values, mmol/L,[mean (IQL)] | 732.4 (662.2: 810.8) | 723.0 (661.5: 820.3) | 0.83 | 752.7 (674.3: 834.5) | 743.24 (690.5: 855.4) | 0.59 |
AUC = area under the curve; GDM = gestational diabetes mellitus; IADPSG= International Association of Diabetes and Pregnancy Study Groups; OGTT= oral glucose tolerance test; SD= standard deviation; IQL = Interquartile limits. All values are derived from an ITT analysis. Between group differences was done using two-sample t-test or Fishers exact test.